2025 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care

• Despite advances in treatment, incidence of cardiac arrest remains high, and survival remains low. The incidence of emergency medical services (EMS)–treated, OHCA in people of any age in the United States was 378.7 individuals per 100 000 population, with great variation in incidence and survival between states. Survival to hospital discharge for OHCA is approximately 10.5%, while in-hospital cardiac arrest survival is approximately 23.6% (adults) and 45.2% (children).
• The purpose of the guidelines is to provide best practice recommendations in cardiopulmonary resuscitation and emergency cardiovascular care. These guidelines provide an update to the recommendations in the 2020 guidelines and provide new recommendations to topics where recommendations previously did not exist.
• The guidelines provide guidance for lay rescuers and healthcare professionals in the treatment of neonates, pediatrics, and adults. Chapter topics include systems of care, neonatal life support, adult and pediatric basic and advanced life support, post-cardiac arrest care, special circumstances, education and training, and ethics.

See the full Guideline in Circulation

Part 1: Executive summary

Part 2: Evidence evaluation and guidelines development

Part 3: Ethics

Part 4: Systems of Care

Part 5: Neonatal Resuscitation

Part 6: Pediatric Basic Life Support

Part 7: Adult Basic Life Support

Part 8: Pediatric Advanced Life Support

Part 9: Adult Advanced Life Support

Part 10: Adult and Pediatric Special Circumstances of Resuscitation

Part 11: Post–Cardiac Arrest Care

Part 12: Resuscitation Education Science